First, collect all the required ingredients according to the ingredient list.
Preheat oven at 120°C and line a baking sheet over the oven plate.
Meanwhile, combine corn Chex, rice Chex, wheat Chex, pretzels, and nuts in a large bowl.
Now, melt butter over medium heat and add Worcestershire sauce, hot sauce, garlic powder, paprika, cayenne, and salt to make the spicy butter.
Then, add the spicy butter over the Chex Mix and toss well to coat evenly.
After that, spread them on baking sheet and bake for 45 minutes.
Stir them every 15 minutes to avoid burning.
After 45 minutes of baking, turn of the switch.
Completely cool the spicy Chex Mix.
Lastly, serve it as a snack or store in airtight container.