First, collect and measure all the required ingredients.
Secondly, combine ketchup, brown sugar, vinegar, molasses, Worcestershire sauce, and the secret ingredient, which is the Hickory liquid smoke in a saucepan over medium heat.
Thirdly, add onion powder, garlic powder, smoked paprika, salt, and cayenne powder into the sauce base and stir nicely.
Fourthly, add some water to loosen the consistency, then simmer the sauce for 10 – 15 minutes. Stir occasionally in this step.
Fifthly, taste the sauce and adjust the ingredients if required.
Lastly, the sauce is ready. Transfer the sauce from the saucepan to a bowl and let it cool at room temperature. Then, you can enjoy the sauce.
To store the sauce, pour it in a glass bottle, air tight it, and refrigerate the sauce.